Publications

▸ 2026 8 entries

Lead Projects

J. Sung¹, Y. Seo¹, J.Y. Lee (¹equally contributed)

From Undruggable to Degradable: Strategic Expansion of Targeted Protein Degradation in Cancer Therapy

Molecular Therapy in press · 2026

S.Y. Yoo¹, Y.J. Kim¹, G. Kim, J.M. Koo, J.W. Yu, S.M. Lee, E.J. Park, T. Kim, S. Koh, W.H. Cho, A. Sapkota, H.S. Choi, J. Koo, Y.L. Cho, D. Lee, E.K. Jo^*, J.Y. Lee^* (¹equally contributed, *co-correspondence)

Inhalable nanohybrid of delpazolid enhances antimicrobial host defense against mycobacterial pulmonary infection ↗

Journal of Controlled Release 395, 114950 · 2026

S.Y. Yoo¹, J. Kim¹, S.M. Lee, S. Lee, T. Kim, J. Kang, L.B.H. Pham, H. Lim, M. Kim, K.Y. Lim, J. Lee^*, J.Y. Lee^* (¹equally contributed, *co-correspondence)

Dual-Light-Primed GSH-Scavenging Lipid Hybrid Nanoplatform for Cascade-Activated Photodynamic Therapy ↗

Small 22(18), e12546 · 2026 Front Cover

Y. Seo¹, J. Sung¹, J.Y. Lee (¹equally contributed)

From permeation enhancer to therapeutic enabler: advances, applications, and translational perspectives in hyaluronidase-based drug delivery ↗

Materials Today Bio 38, 103052 · 2026

H.S. Lee¹, S. Choo¹, M. Chaudhary, J.H. Park, J. Chang, Y. Byun, K.T. Kim^*, J.Y. Lee^* (¹equally contributed, *co-correspondence)

Benchmarking protein nanoparticles for drug delivery and clinical translation ↗

Small Methods 10(3), e01671 · 2026

Contributing Projects

D. Chaudhary, R. Kausar, J. Lee, M. Shrestha, J. Park, Y.S. Youn, J.O. Kim, J.Y. Lee, J.Y. Kim^*, S. Yook^*, J.H. Jeong^* (*co-correspondence)

Bioengineered hybrid spheroids integrating mesenchymal stem cells and metformin-loaded microspheres for the treatment of sepsis-induced liver injury ↗

Journal of Controlled Release 393, 114798 · 2026

M. Shrestha¹, Y. Kim¹, S. Park, H.L. Jiang, J.Y. Lee, D. Kim^*, J.H. Jeong^* (¹equally contributed, *co-correspondence)

eVLP-Mediated Cas9 delivery for preventing IBMIR in islet transplantation ↗

Small 22(1), e08128 · 2026

L.B.H. Pham¹, T. Kim¹, S. Kim, Y.S. Kim, J. Kim, K. Kim, H. Lim, W.S. Shim, B. Kim, S.Y. Yoo, J.Y. Lee, M. Choi, W. Kim, K.W. Kang^*, J. Lee^* (¹equally contributed, *co-correspondence)

Novel near-infrared probe for monitoring lipid peroxidation-mediated viscosity change in ferroptotic hepatocytes ↗

Clinical and Molecular Hepatology 32(1), 318–338 · 2026

▸ 2025 5 entries

Lead Projects

S.M. Lee, S.Y. Yoo, T. Kim, N. Kim, J. Kang, K.Y. Lim, M. Kim, S. Choo, H.S. Lee, H. Kim, N.W. Kang, M. Chaudhary, K. Bikram, W. Lee, C.W. Cho, D.D. Kim, K.T. Kim^*, J.Y. Lee^* (*co-correspondence)

Radiopaque hydrogel-in-liposomes towards theranostic applications for malignant tumors ↗

Biomedicine & Pharmacotherapy 183, 117822 · 2025

M.J. Baek¹, S.M. Lee¹, D.D. Kim^*, J.Y. Lee^* (¹equally contributed, *co-correspondence)

Breakthroughs in deep tumour penetrating nano-phototheranostics for tumour ablation ↗

Clinical and Translational Medicine 15, e70188 · 2025

W.H. Cho¹, H. Kim¹, S.Y. Yoo¹, S.M. Lee, T. Kim, J.Y. Lee (¹equally contributed)

Advancements in uricase formulations: overcoming therapeutic challenges in enzyme replacement therapy ↗

Journal of Pharmaceutical Investigation 55, 521–556 · 2025

H. Kim¹, H.S. Lee¹, J.H. Ahn, T.W. Kwon, S.Y. Yoo, D. Seo, S.K. Kim, H.H. Park, S.W. Cho^*, W. Lee^*, J.Y. Lee^*, H.N. Kim^* (¹equally contributed, *co-correspondence)

Targeted nanocomplex delivery for protecting vascular integrity and enhancing anticancer effects in hepatocellular carcinoma ↗

Small Science 6, e202400616 · 2025 Front Cover

Contributing Projects

J. Kim¹, D. Seo¹, S.Y. Yoo, H.J. Lee, J. Kim, J.E. Yeom, J.Y. Lee, W. Park^*, K.S. Hong^*, W. Lee^* (¹equally contributed, *co-correspondence)

Lung-homing nanoliposomes for early intervention in NETosis and inflammation during acute lung injury ↗

Nano Convergence 12, 8 · 2025

▸ 2024 4 entries

Lead Projects

D.T. Nguyen¹, M.J. Baek¹, S.M. Lee, D. Kim, S.Y. Yoo, J.Y. Lee^*, D.D. Kim^* (¹equally contributed, *co-correspondence)

Photobleaching-mediated charge-convertible cyclodextrin nanoparticles achieve deep tumour penetration for rectal cancer theranostics ↗

Nature Nanotechnology 19, 1723–1734 · 2024 News & Views

S.Y. Yoo¹, H.Y. Kim¹, D.H. Kim, W.S. Shim, S.M. Lee, D.H. Lee, J.M. Koo, J.H. Yoo, S. Koh, J.C. Park, J. Yu, J.S. Jeon, M.J. Baek, D.D. Kim, J.Y. Lee, S.J. Oh, S.K. Kim^*, J.Y. Lee^*, K.W. Kang^* (¹equally contributed, *co-correspondence)

Laser-responsive erastin-loaded chondroitin sulfate nanomedicine targeting CD44 and system xc⁻ in liver cancer: a non-ferroptotic approach ↗

Journal of Controlled Release 375, 574–588 · 2024

Contributing Projects

L.B.H. Pham, K.L. Chung, S.Y. Yoo, S. Kim, B. Lim, J.Y. Lee, J. Lee

Sequential induction of ferroptosis and pyroptosis in cancer cells by lipid droplet-targeting AIE theranostics ↗

Chemical Engineering Journal 498, 155439 · 2024

H.E. Kim, Y.G. Na, M. Jin, B. Song, T.S. Yun, Y.R. Hwang, J.S. Park, J.Y. Lee, J.S. Baek, S.C. Han, H.K. Lee, C.W. Cho

Fabrication and evaluation of chitosan-coated nanostructured lipid carriers for co-delivery of paclitaxel and PD-L1 siRNA ↗

International Journal of Pharmaceutics 666, 124835 · 2024

▸ 2017 – 2023 Assistant & Associate Professor, CNU 60 entries

Lead Projects

M.J. Baek, D.T. Nguyen, D. Kim, S.Y. Yoo, S.M. Lee, J.Y. Lee^*, D.D. Kim^* (*co-correspondence)

Tailoring renal clearable zwitterionic cyclodextrin for colorectal cancer-selective drug delivery

Nature Nanotechnology 18(8), 945–956 · 2023

S.Y. Yoo, Y.H. Mun, N.W. Kang, J.M. Koo, D.H. Lee, J.H. Yoo, S.M. Lee, S. Koh, J.C. Park, T. Kim, E.K. Shin, H.S. Lee, J. Sim, K.W. Kang, S.K. Kim, C.W. Cho, M.G. Kim^*, D.D. Kim^*, J.Y. Lee^* (*co-correspondence)

Enhancement of the therapeutic efficacy of the MAP regimen using thiamine pyrophosphate-decorated albumin nanoclusters in osteosarcoma treatment

Bioengineering & Translational Medicine e10472 · 2022

H.S. Lee, S.Y. Yoo, S.M. Lee, N.W. Kang, S.K. Kim, G.Y. Song, D.D. Kim, J.Y. Lee^*

Hypoxia-alleviating hemoglobin nanoclusters for sensitizing chemo-photodynamic therapy of cervical cancer

Chemical Engineering Journal 457, 141224 · 2023

N.W. Kang, V. Visetvichaporn, D.T. Nguyen, E.K. Shin, D.H. Kim, M.J. Kim, S.Y. Yoo, J.Y. Lee^*, D.D. Kim^* (*co-correspondence)

Bone tumor-homing nanotherapeutics for prolonged retention in tumor microenvironment and facilitated apoptotic process via mevalonate pathway inhibition

Materials Today Bio 19, 100591 · 2023

N.W. Kang, J.Y. Lee^*, D.D. Kim^* (*co-correspondence)

Hydroxyapatite-binding albumin nanoclusters for enhancing bone tumor chemotherapy

Journal of Controlled Release 342, 111–121 · 2022

H.H. Park, H. Kim, H.S. Lee, E.U. Seo, J.E. Kim, J.H. Lee, Y.H. Mun, S.Y. Yoo, J. An, M.Y. Yun, N.W. Kang, D.D. Kim, D.H. Na, K.S. Hong, J.G. Jang, J.H. Ahn, J.S. Bae^*, G.Y. Song^*, J.Y. Lee^*, H.N. Kim^*, W. Lee^* (*co-correspondence)

PEGylated nanoparticle albumin-bound steroidal ginsenoside derivatives ameliorate SARS-CoV-2-mediated hyper-inflammatory responses

Biomaterials 273, 120827 · 2021

J.Y. Lee^*, Y.S. Lee^*, D.H. Kim, H.S. Lee, B.R. Yang, M.G. Kim (*equally contributed)

The use of social media in detecting drug safety-related new black box warnings, labeling changes, or withdrawals: scoping review

JMIR Public Health and Surveillance 7(6), e30137 · 2021

H.S. Lee, N.W. Kang, H. Kim, D.H. Kim, J.W. Chae, W. Lee, G.Y. Song, C.W. Cho, D.D. Kim, J.Y. Lee^*

Chondroitin sulfate-hybridized zein nanoparticles for tumor-targeted delivery of docetaxel

Carbohydrate Polymers 253, 117187 · 2021

W. Lee^*, J.Y. Lee^*, H.S. Lee, Y. Yoo, H. Shin, H. Kim, D.S. Min, J.S. Bae, Y.K. Seo (*equally contributed)

Thermosensitive hydrogel harboring CD146/IGF-1 nanoparticles for skeletal-muscle regeneration

ACS Applied Bio Materials 4(9), 7070–7080 · 2021

H. Kim, H.S. Lee, J.H. Ahn, K.S. Hong, J.G. Jang, J. An, Y.H. Mun, S.Y. Yoo, Y.J. Choi, M.Y. Yun, G.Y. Song, J. Joo, D.H. Na^*, H.N. Kim^*, H.H. Park^*, J.Y. Lee^*, W. Lee^* (*co-correspondence)

Lung-selective 25-hydroxycholesterol nanotherapeutics as a suppressor of COVID-19-associated cytokine storm

Nano Today 38, 101149 · 2021

B. Khadka^*, J.Y. Lee^*, E.K. Park, K.T. Kim, J.S. Bae (*equally contributed)

Impacts of drug interactions on pharmacokinetics and the brain transporters: a recent review of natural compound–drug interactions in brain disorders

International Journal of Molecular Sciences 22(4) · 2021

J.Y. Lee, H.S. Lee, N.W. Kang, S.Y. Lee, D.H. Kim, S. Kim, I.S. Yoon, H.J. Cho, D.D. Kim

Blood component ridable and CD44 receptor targetable nanoparticles based on a maleimide-functionalized chondroitin sulfate derivative

Carbohydrate Polymers 230, 115568 · 2020

H.S. Lee, J.J. Lee, M.G. Kim, K.T. Kim, C.W. Cho, D.D. Kim, J.Y. Lee^*

Sprinkle formulations — a review of commercially available products

Asian Journal of Pharmaceutical Sciences 15(3), 292–310 · 2020

D.H. Kim, H.S. Lee, Y.H. Mun, S. Koh, J.S. Park, S.M. Lee, N.W. Kang, M.Y. Lee, C.W. Cho, D.D. Kim, J.Y. Lee^*

An overview of chondrosarcoma with a focus on nanoscale therapeutics

Journal of Pharmaceutical Investigation 50, 537–552 · 2020

M.H. Kim, D.H. Kim, D.T. Nguyen, H.S. Lee, N.W. Kang, M.J. Baek, J. An, S.Y. Yoo, Y.H. Mun, W. Lee, K.T. Kim, C.W. Cho, J.Y. Lee^*, D.D. Kim^* (*co-correspondence)

Preparation and evaluation of Eudragit L100-PEG proliponiosomes for enhanced oral delivery of celecoxib

Pharmaceutics 12(8), 165 · 2020

H.G. Kim, H.S. Lee, J.S. Jeon, Y.J. Choi, Y.J. Choi, S.Y. Yoo, E.Y. Kim, K. Lee, I. Park, M. Na, H.J. Park, S.W. Cho, J.H. Kim, J.Y. Lee^*, S.K. Kim^* (*co-correspondence)

Quasi-irreversible inhibition of CYP2D6 by berberine

Pharmaceutics 12(10), 916 · 2020

D.H. Kim, H.S. Lee, T.W. Kwon, Y.M. Han, N.W. Kang, M.Y. Lee, D.D. Kim, M.G. Kim^*, J.Y. Lee^* (*co-correspondence)

Single enzyme nanoparticle, an effective tool for enzyme replacement therapy

Archives of Pharmacal Research 43(1), 1–21 · 2020

N.W. Kang^*, J.Y. Lee^*, K. Song, M.H. Kim, S. Yoon, D.T. Nguyen, S. Kim, Y.S. Kim, D.D. Kim (*equally contributed)

Development and validation of liquid chromatography–tandem mass spectrometry method for pharmacokinetic evaluation of 7β-(3-ethyl-cis-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranon in rats

Molecules 25(8), 1774 · 2020

J.J. Lee, Y.M. Han, T.W. Kwon, D.H. Kim, H.S. Lee, W.J. Jung, J. Kim, S. Kang, S.K. Kim, C.W. Cho, K.R. Lee, D.D. Kim, M.C. Park^*, J.Y. Lee^* (*co-correspondence)

Functional fragments of AIMP1-derived peptide (AdP) and optimized hydrosol for their topical deposition by Box–Behnken design

Molecules 24(10), 1967 · 2019

K.T. Kim^*, J.Y. Lee^*, D.D. Kim, I.S. Yoon, H.J. Cho (*equally contributed)

Recent progress in the development of poly(lactic-co-glycolic acid)-based nanostructures for cancer imaging and therapy

Pharmaceutics 11(6), 280 · 2019

D. Jeon, K.T. Kim, M.J. Baek, D.H. Kim, J.Y. Lee^*, D.D. Kim^* (*co-correspondence)

Preparation and evaluation of celecoxib-loaded proliposomes with high lipid content

European Journal of Pharmaceutics and Biopharmaceutics 141, 139–148 · 2019

K.T. Kim, H.S. Lee, J.J. Lee, E.K. Park, B.S. Lee, J.Y. Lee^*, J.S. Bae^* (*co-correspondence)

Nanodelivery systems for overcoming limited transportation of therapeutic molecules through the blood–brain barrier

Future Medicinal Chemistry 10(22), 2659–2674 · 2018

N.W. Kang, M.H. Kim, S.Y. Sohn, K.T. Kim, J.H. Park, S.Y. Lee, J.Y. Lee^*, D.D. Kim^* (*co-correspondence)

Curcumin-loaded lipid-hybridized cellulose nanofiber film ameliorates imiquimod-induced psoriasis-like dermatitis in mice

Biomaterials 182, 245–258 · 2018

J.Y. Lee, U. Termsarasab, M.Y. Lee, D.H. Kim, S.Y. Lee, J.S. Kim, H.J. Cho, D.D. Kim

Chemosensitizing indomethacin-conjugated chitosan oligosaccharide nanoparticles for tumor-targeted drug delivery

Acta Biomaterialia 57, 262–273 · 2017

J.Y. Lee, J.H. Park, K.T. Kim, J. Yu, P.K. Sahu, N. Kang, H.J. Shin, M.H. Kim, J.S. Kim, I.S. Yoon, L.S. Jeong, D.D. Kim

Determination and validation of LJ-2698, a potent human A(3) adenosine receptor antagonist, in rat plasma by liquid chromatography–tandem mass spectrometry and its application in pharmacokinetic study

Archives of Pharmacal Research 40(8), 952–961 · 2017

Contributing Projects

D. Kwak, J. Lee, J. Kim, et al.

Nitric oxide-releasing albumin nanoclusters facilitate healing of methicillin-resistant Staphylococcus aureus-infected cutaneous wounds

Journal of Pharmaceutical Investigation 54, 51–60 · 2024

T.N. Nguyen, S.Y. Yoo, W. Tangchang, J.Y. Lee, H.Y. Son, J.S. Park

Sustained delivery of triamcinolone acetonide from a thermosensitive microemulsion gel system for the treatment of sensorineural hearing loss

Drug Delivery 30(1), 2242003 · 2023

N.P. Tran, P. Tran, S.Y. Yoo, W. Tangchang, S. Lee, J.Y. Lee, H.Y. Son, J.S. Park

Sialic acid-decorated liposomes enhance the anti-cancer efficacy of docetaxel in tumor-associated macrophages

Biomaterials Advances 154, 213606 · 2023

H.S. Kim, E. Jang, H.I. Kim, M. Hari Babu, J.Y. Lee, S.K. Kim, J. Sim

Chemical glycosylation with p-methoxyphenyl (PMP) glycosides via oxidative activation

Organic Letters 25(19), 3471–3475 · 2023

Y. Liu, R. Naskar, S. Acharya, L. Ba Vinh, J.H. Kim, J.Y. Lee, Y.H. Kim, J.S. Kang, I. Hwang

Inotodiol, an antiasthmatic agent with efficacy and safety, preferentially impairs membrane-proximal signaling for mast cell activation

International Immunopharmacology 117, 109854 · 2023

B.R. Yang, J.Y. Lee, M.G. Kim

The risk of pulmonary adverse drug reactions of rebamipide and other drugs for acid-related diseases: an analysis of the national pharmacovigilance database in South Korea

Journal of Digestive Diseases 23(2), 118–123 · 2022

T.M.A. Pham, D.H. Lee, Y.G. Na, M. Jin, M. Jung, H.E. Kim, H. Yoo, J.H. Won, J.Y. Lee, J.S. Baek, S.C. Han, H.K. Lee, C.W. Cho

Enhancement of S(+)-zaltoprofen oral bioavailability using nanostructured lipid carrier system

Archives of Pharmacal Research 45(11), 822–835 · 2022

L.T. Ngo, S.Y. Yang, S. Shin, D.T. Cao, H. Van Nguyen, S. Jung, J.Y. Lee, J.H. Lee, H.Y. Yun, J.W. Chae

Application of physiologically-based pharmacokinetic model approach to predict pharmacokinetics and drug–drug interaction of rivaroxaban: a case study of rivaroxaban and carbamazepine

CPT: Pharmacometrics & Systems Pharmacology 11(11), 1430–1442 · 2022

H. Lee, M. Choi, H.E. Kim, M. Jin, W.J. Jeon, M. Jung, H. Yoo, J.H. Won, Y.G. Na, J.Y. Lee, H. Seong, H.K. Lee, C.W. Cho

Mannosylated poly(acrylic acid)-coated mesoporous silica nanoparticles for anticancer therapy

Journal of Controlled Release 349, 241–253 · 2022

Y.Y. Lee, H.H. Park, W. Park, H. Kim, J.G. Jang, K.S. Hong, J.Y. Lee, H.S. Seo, D.H. Na, T.H. Kim, Y.B. Choy, J.H. Ahn, W. Lee, C.G. Park

Long-acting nanoparticulate DNase-1 for effective suppression of SARS-CoV-2-mediated neutrophil activities and cytokine storm

Biomaterials 267, 120389 · 2021

H. Lee, J.B. Bang, Y.G. Na, J.Y. Lee, C.W. Cho, J.S. Baek, H.K. Lee

Development and evaluation of tannic acid-coated nanosuspension for enhancing oral bioavailability of curcumin

Pharmaceutics 13(9), 1460 · 2021

M.K. Kim, D.H. Ki, Y.G. Na, H.S. Lee, J.S. Baek, J.Y. Lee, H.K. Lee, C.W. Cho

Optimization of mesoporous silica nanoparticles through statistical design of experiment and the application for the anticancer drug

Pharmaceutics 13(2), 184 · 2021

D.H. Kim, T.N. Nguyen, Y.M. Han, P. Tran, J. Rho, J.Y. Lee, H.Y. Son, J.S. Park

Local drug delivery using poly(lactic-co-glycolic acid) nanoparticles in thermosensitive gels for inner ear disease treatment

Drug Delivery 28(1), 2268–2277 · 2021

N.W. Kang, S.Y. Yoon, S. Kim, N.Y. Yu, J.H. Park, J.Y. Lee, H.J. Cho, D.D. Kim

Subcutaneously injectable hyaluronic acid hydrogel for sustained release of donepezil with reduced initial burst release: effect of hybridization of microstructured lipid carriers and albumin

Pharmaceutics 13(6), 864 · 2021

N.W. Kang, S. Kim, J.Y. Lee, K.T. Kim, Y. Choi, Y. Oh, J. Kim, D.D. Kim, J.H. Park

Microneedles for drug delivery: recent advances in materials and geometry for preclinical and clinical studies

Expert Opinion on Drug Delivery 18(7), 929–947 · 2021

J.S. Park, J.Y. Lee, Y.T.K. Nguyen, N.W. Kang, E.K. Oh, D.M. Jang, H.J. Kim, D.D. Kim, B.W. Han

Structural analyses on the deamidation of N-terminal Asn in the human N-degron pathway

Biomolecules 10(1), 163 · 2020

J.H. Park, M.J. Baek, J.Y. Lee, K.T. Kim, H.J. Cho, D.D. Kim

Preparation and characterization of sorafenib-loaded microprecipitated bulk powder for enhancing oral bioavailability

International Journal of Pharmaceutics 589, 119836 · 2020

S.J. Kim, B. Park, H.W. Huh, Y.G. Na, M. Kim, M. Han, H. Lee, T.M.A. Pham, H.K. Lee, J.Y. Lee, C.S. Kim, J.S. Baek, C.W. Cho

Achyranthis radix extract-loaded eye drop formulation development and novel evaluation method for dry eye treatment

Pharmaceutics 12(2) · 2020

M.H. Kim, Y.E. Jeon, S. Kang, J.Y. Lee, K.W. Lee, K.T. Kim, D.D. Kim

Lipid nanoparticles for enhancing the physicochemical stability and topical skin delivery of orobol

Pharmaceutics 12(9), 845 · 2020

M.G. Kim, I. Yang, H.S. Lee, J.Y. Lee, K. Kim

Lipid-modifying effects of krill oil vs fish oil: a network meta-analysis

Nutrition Reviews 78(9), 699–708 · 2020

B. Khadka, J.Y. Lee, D.H. Park, K.T. Kim, J.S. Bae

The role of natural compounds and their nanocarriers in the treatment of CNS inflammation

Biomolecules 10(10), 1401 · 2020

B. Khadka, J.Y. Lee, K.T. Kim, J.S. Bae

Recent progress in therapeutic drug delivery systems for treatment of traumatic CNS injuries

Future Medicinal Chemistry 12(19), 1759–1778 · 2020

Y.J. Chae, Y.K. Song, S.H. Chae, M.J. Kim, J.S. Kang, J.Y. Lee, T.S. Koo, K.R. Lee

Development and validation of an LC–MS/MS method for monitoring larotrectinib, a tropomyosin-related kinase inhibitor, in mouse and human plasma and application to pharmacokinetic studies

Journal of Analytical Science and Technology 11(1), 20 · 2020

S.J. Kim, Y.G. Na, H.K. Lee, H.J. Lee, M. Wang, H.W. Huh, H.S. Lee, J.Y. Lee, C.W. Cho

Stability evaluation of H3N2 influenza split vaccine in drying process for solidification

Journal of Pharmaceutical Investigation 50, 107–113 · 2020

M.H. Kim, K.T. Kim, S.Y. Sohn, J.Y. Lee, C.H. Lee, H. Yang, B.K. Lee, K.W. Lee, D.D. Kim

Formulation and evaluation of nanostructured lipid carriers (NLCs) of 20(S)-protopanaxadiol (PPD) by Box–Behnken design

International Journal of Nanomedicine 14, 8509–8520 · 2019

J.Y. Kim, S. Lee, Y. Kim, E.J. Jeong, I.H. Lee, M.H. Son, J.Y. Lee, S.K. Kim, K.S. Moon

Subacute toxicity and toxicokinetics study of DHP107, an oral paclitaxel formulation with once-weekly dosing in mice

Regulatory Toxicology and Pharmacology 103, 196–204 · 2019

G.H. Son, H.J. Lee, Y.G. Na, H.K. Lee, S.J. Kim, H.W. Huh, K.T. Kim, J.S. Kang, Y.H. Kim, C.S. Myung, M.H. Yoon, S.J. Kim, H.S. Cho, J.Y. Lee, C.W. Cho

Formulation and statistical analysis of an herbal medicine tablet containing Morus alba leaf extracts

Journal of Pharmaceutical Investigation 49, 625–634 · 2019

J.S. Kim, K.T. Kim, J.H. Park, J.Y. Lee, M. Kim, H.G. Min, I.H. Moon, C.Y. Choi, B.H. Kim, D.D. Kim

Coacervate microcapsules of vitamin U optimized by central composite design (CCD)

Journal of Pharmaceutical Investigation 49, 313–321 · 2019

J.H. Park, J.Y. Lee, K.T. Kim, H.E. Joe, H.J. Cho, Y.K. Shin, D.D. Kim

Physostigmine-loaded liposomes for extended prophylaxis against nerve agent poisoning

International Journal of Pharmaceutics 553(1–2), 467–473 · 2018

S.Y. Lee, J.W. Choi, J.Y. Lee, D.D. Kim, H.C. Kim, H.J. Cho

Hyaluronic acid/doxorubicin nanoassembly-releasing microspheres for the transarterial chemoembolization of a liver tumor

Drug Delivery 25(1), 1472–1483 · 2018

K.T. Kim, M.H. Kim, J.H. Park, J.Y. Lee, H.J. Cho, I.S. Yoon, D.D. Kim

Microemulsion-based hydrogels for enhancing epidermal/dermal deposition of topically administered 20(S)-protopanaxadiol: in vitro and in vivo evaluation studies

Journal of Ginseng Research 42(4), 512–523 · 2018

K.T. Kim, J. Lee, M.H. Kim, J.H. Park, J.Y. Lee, J.H. Song, M. Jung, M.H. Jang, H.J. Cho, I.S. Yoon, D.D. Kim

Novel reverse electrodialysis-driven iontophoretic system for topical and transdermal delivery of poorly permeable therapeutic agents

Drug Delivery 24(1), 1204–1215 · 2017

K.T. Kim, J.S. Kim, M.H. Kim, J.H. Park, J.Y. Lee, W. Lee, K.K. Min, M.G. Song, C.Y. Choi, W.S. Kim, H.K. Oh, D.D. Kim

Effect of enhancers on in vitro and in vivo skin permeation and deposition of S-methyl-(L)-methionine

Biomolecules & Therapeutics 25(4), 434–440 · 2017

J.H. Kim, J.S. Baek, J.K. Park, B.J. Lee, M.S. Kim, S.J. Hwang, J.Y. Lee, C.W. Cho

Development of Houttuynia cordata extract-loaded solid lipid nanoparticles for oral delivery: high drug loading efficiency and controlled release

Molecules 22(12), 2215 · 2017

B.S. Kim, Y.G. Na, J.H. Choi, I. Kim, E. Lee, S.Y. Kim, J.Y. Lee, C.W. Cho

The improvement of skin whitening of phenylethyl resorcinol by nanostructured lipid carriers

Nanomaterials 7(9), 241 · 2017

▸ 2011 – 2017 Pre-faculty Years 22 entries

Lead Projects

J.Y. Lee^*, U. Termsarasab^*, J.H. Park, S.Y. Lee, S.H. Ko, J.S. Shim, S.J. Chung, H.J. Cho, D.D. Kim (*equally contributed)

Dual CD44 and folate receptor-targeted nanoparticles for cancer diagnosis and anticancer drug delivery

Journal of Controlled Release 236, 38–46 · 2016

J.Y. Lee, J.H. Song, I.S. Yoon, H.J. Ko, D.D. Kim, H.J. Cho

Determination of manassantin B in rat plasma using a high performance liquid chromatography with fluorescence detection and its quantitative application to pharmacokinetic study

Journal of Chromatography B 1011, 121–127 · 2016

J.Y. Lee, J.H. Park, J.J. Lee, S.Y. Lee, S.J. Chung, H.J. Cho, D.D. Kim

Polyethylene glycol-conjugated chondroitin sulfate A derivative nanoparticles for tumor-targeted delivery of anticancer drugs

Carbohydrate Polymers 151, 68–77 · 2016

J.Y. Lee, S.B. Kim, J. Chun, K.H. Song, Y.S. Kim, S.J. Chung, H.J. Cho, I.S. Yoon, D.D. Kim

High body clearance and low oral bioavailability of alantolactone, isolated from Inula helenium, in rats: extensive hepatic metabolism and low stability in gastrointestinal fluids

Biopharmaceutics & Drug Disposition 37(3), 156–167 · 2016

J.Y. Lee, S.J. Chung, H.J. Cho, D.D. Kim

Iodinated hyaluronic acid oligomer-based nanoassemblies for tumor-targeted drug delivery and cancer imaging

Biomaterials 85, 218–231 · 2016

J.Y. Lee, S.J. Chung, H.J. Cho, D.D. Kim

Phenylboronic acid-decorated chondroitin sulfate A-based theranostic nanoparticles for enhanced tumor targeting and penetration

Advanced Functional Materials 25(24), 3705–3717 · 2015

J.Y. Lee, M.Y. Lee, M.W. Ha, T.H. Won, H.J. Cho, J. Shin, H.G. Park, D.D. Kim

Determination and validation of psammaplin A and its derivatives in rat plasma by liquid chromatography–tandem mass spectrometry and its application in pharmacokinetic study

Journal of Chromatography B 1000, 155–162 · 2015

J.Y. Lee, W.S. Kang, J. Piao, I.S. Yoon, D.D. Kim, H.J. Cho (equally contributed)

Soluplus®/TPGS-based solid dispersions prepared by hot-melt extrusion equipped with twin-screw systems for enhancing oral bioavailability of valsartan

Drug Design, Development and Therapy 9, 2745–2756 · 2015

J.Y. Lee, S.J. Chung, H.J. Cho, D.D. Kim

Bile acid-conjugated chondroitin sulfate A-based nanoparticles for tumor-targeted anticancer drug delivery

European Journal of Pharmaceutics and Biopharmaceutics 94, 532–541 · 2015

J.Y. Lee, H. Yang, I.S. Yoon, S.B. Kim, S.H. Ko, J.S. Shim, S.H. Sung, H.J. Cho, D.D. Kim

Nanocomplexes based on amphiphilic hyaluronic acid derivative and polyethylene glycol-lipid for ginsenoside Rg3 delivery

Journal of Pharmaceutical Sciences 103(10), 3254–3262 · 2014

J.Y. Lee, J.S. Kim, H.J. Cho, D.D. Kim

Poly(styrene)-b-poly(DL-lactide) copolymer-based nanoparticles for anticancer drug delivery

International Journal of Nanomedicine 9, 2803–2813 · 2014

Contributing Projects

J.Y. Jeong, E.H. Hong, S.Y. Lee, J.Y. Lee, J.H. Song, S.H. Ko, J.S. Shim, S. Choe, D.D. Kim, H.J. Ko, H.J. Cho

Boronic acid-tethered amphiphilic hyaluronic acid derivative-based nanoassemblies for tumor targeting and penetration

Acta Biomaterialia 53, 414–426 · 2017

S.Y. Lee, J.J. Lee, J.H. Park, J.Y. Lee, S.H. Ko, J.S. Shim, J. Lee, M.Y. Heo, D.D. Kim, H.J. Cho

Electrosprayed nanocomposites based on hyaluronic acid derivative and Soluplus for tumor-targeted drug delivery

Colloids and Surfaces B: Biointerfaces 145, 267–274 · 2016

J.H. Park, H.J. Shin, M.H. Kim, J.S. Kim, N. Kang, J.Y. Lee, K.T. Kim, J.I. Lee, D.D. Kim

Application of montmorillonite in bentonite as a pharmaceutical excipient in drug delivery systems

Journal of Pharmaceutical Investigation 46(4), 363–375 · 2016

J.J. Lee, J.H. Park, J.Y. Lee, J.Y. Jeong, S.Y. Lee, I.S. Yoon, W.S. Kang, D.D. Kim, H.J. Cho

Omega-3 fatty acids incorporated colloidal systems for the delivery of Angelica gigas Nakai extract

Colloids and Surfaces B: Biointerfaces 140, 239–245 · 2016

J.J. Lee, S. Nam, J.H. Park, S.Y. Lee, J.Y. Jeong, J.Y. Lee, W.S. Kang, I.S. Yoon, D.D. Kim, H.J. Cho

Nanocomposites based on Soluplus and Angelica gigas Nakai extract fabricated by an electrohydrodynamic method for oral administration

Journal of Colloid and Interface Science 484, 146–154 · 2016

K.T. Kim, J.Y. Lee, J.H. Park, M.H. Kim, J.S. Kim, H.J. Shin, N. Kang, H.J. Cho, I.S. Yoon, D.D. Kim

Development of HPLC method for the determination of buspirone in rat plasma using fluorescence detection and its application to a pharmacokinetic study

Chemical & Pharmaceutical Bulletin 64(11), 1582–1588 · 2016

P.K. Sahu, T. Umme, J. Yu, A. Nayak, G. Kim, M. Noh, J.Y. Lee, D.D. Kim, L.S. Jeong

Selenoacyclovir and selenoganciclovir: discovery of a new template for antiviral agents

Journal of Medicinal Chemistry 58(21), 8734–8738 · 2015

J. Piao, J.Y. Lee, J.B. Weon, C.J. Ma, H.J. Ko, D.D. Kim, W.S. Kang, H.J. Cho

Angelica gigas Nakai and Soluplus-based solid formulations prepared by hot-melting extrusion: oral absorption enhancing and memory ameliorating effects

PLoS One 10(4), e0124447 · 2015

J.H. Park, J.Y. Lee, U. Termsarasab, I.S. Yoon, S.H. Ko, J.S. Shim, H.J. Cho, D.D. Kim

Development of poly(lactic-co-glycolic) acid nanoparticles-embedded hyaluronic acid–ceramide-based nanostructure for tumor-targeted drug delivery

International Journal of Pharmaceutics 473(1–2), 426–433 · 2014

J.H. Park, H.J. Cho, U. Termsarasab, J.Y. Lee, S.H. Ko, J.S. Shim, I.S. Yoon, D.D. Kim

Interconnected hyaluronic acid derivative-based nanoparticles for anticancer drug delivery

Colloids and Surfaces B: Biointerfaces 121, 380–387 · 2014

D.H. Kim, U. Termsarasab, H.J. Cho, I.S. Yoon, J.Y. Lee, H.T. Moon, D.D. Kim

Preparation and characterization of self-assembled nanoparticles based on low-molecular-weight heparin and stearylamine conjugates for controlled delivery of docetaxel

International Journal of Nanomedicine 9, 5711–5727 · 2014